(In-vitro Swedish Study)\r\rAn accepted and published Swedish study demonstrates for the first time the presence of Pfizer-BionTech vaccine DNA in the cell. Mitogen Activated Protein Kinase (MAPK) Activation, p53, and Autophagy Inhibition Characterize the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein Induced Neurotoxicity. 2022 Dec 9;14(12):e32361. The study authors clarified their research in a Q&A in March after it received significant attention, stating this study does not investigate whether the Pfizer vaccine alters our genome, and that there is no reason for anyone to change their decision to take the vaccine based on this study.. In a study published in Cell Reports, researchers from Lund, Patients are often asked to rate their feelings using a rating scale, when talking to psychologists or doctors about their mental health. Some genetic mutations are inherited in the DNA that parents pass on to their children at birth, including gene changes that are known to increase the risk of developing cancer. This, of course, does not mean these data are not important. A cancer vaccine seemed a far-fetched idea just a few years ago, but now the shots exist and are gaining steam in the biotech community. A segment of the protein called the open reading frame-1, or ORF-1, then goes back into the nucleus, where it attaches to the vaccines mRNA and reverse transcribes into spike DNA. We detected high levels of BNT162b2 in Huh7 cells and changes in gene expression of long interspersed nuclear element-1 (LINE-1), which is an endogenous reverse transcriptase. We saw that there was DNA converted from the vaccine's mRNA in the host cells we studied. It is reverse transcribed by LINE-1 proteins of the cells. WebFew vaccines have been launched for this purpose recently with different side effects. For these reasons, while the changes related to LINE-1 are interesting, we cant be sure the effects would be the same in a non-cancerous cell line. The experiment was conducted in a petri dish and aimed to answer the question of whether the mRNA in the vaccine could be converted to DNA. Read more about our fact-checking work here . Our publication is the first in vitro study on the conversion of mRNA vaccine into DNA, inside cells of human origin. It is the three-dimensional (3D) structure. (. (AP Photo/Jae C. Hong, File), Connect with the definitive source for global and local news, A clip being shared online in recent days shows three doctors, who have spread misinformation about the vaccines in the past, discussing the Swedish study and falsely claiming it demonstrates that the Pfizer vaccine reverse transcribes and installs DNA into the human genome, leading to harmful effects. May 03, 2022 These findings were observed in petri dishes under experimental conditions, but we do not yet know if the converted DNA is integrated into the cells DNA in the genome - and if so, if it has any consequences, Rasmussen says in the article. This in itself motivates the need for further studies. Epub 2021 Nov 10. As such, even if DNA representing the viral RNA was integrated into the cell, no other cells with the altered DNA would be produced. Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine breakthrough infections: a multicentre cohort study. This means that what is seen in these cells may not be representative of what would happen in non-cancerous liver cells (or even a different line of cancerous liver cells). Privacy policy in doi: 10.1503/cmaj.211881. Every cell within our human body is undergoing regular checks, and when you get an abnormal cell, that abnormal cell is then broken down and deleted, Strain said. This article was produced by the Reuters Fact Check team. followers 26 videos. Parents PACK. The Swedish study suggests the vaccine is capable of becoming DNA, which is what the CDC claimed See this image and copyright information in PMC. -. And this could be seen with natural virus infection as well, Moore said. This is 1 replication competent plasmid per 350 mRNA molecules and equates to billions of antibiotic resistant plasmids injected per person per shot . Click here:\rhttps://www.drbeen.com/yt-special-p/\r\rWant to support this work? The antibody binds to the pathogen, but instead of blocking it from entering cells, it facilitates entry of the pathogen into cells. They are not sure if it gets integrated in our DNA or not. BNT162b2 is another name for the Pfizer-BioNTech COVID-19 vaccine that is marketed under the brand name Comirnaty. Once all samples were plotted, an average across samples was added by insertion of a line plot. Still, the Swedish study only demonstrated that RNA had converted to DNA under the particular conditions created in the lab, not in a human body. YDM: This study does not investigate whether the Pfizer vaccine alters our genome. Our publication is the first in vitro study on the conversion of mRNA vaccine into DNA, inside cells of human origin. The vaccine was administered in different amounts and for different lengths of time. Two of the authors, Associate Professor Yang de Marinis (YDM) and Professor Magnus Rasmussen (MR), share their views. (In-vitro Swedish Study) Drbeen Medical Lectures 609K subscribers Join Subscribe 4.3M views Streamed 11 Its 5 Notably, mutations in the BRCA tumor-suppressor genes can be inherited. "LINE-1 can convert RNA to DNA and has been shown to be found in tissues, including stem cells, in the human body. Sudden deaths of Canadian Differences in mRNA-1273 (Moderna) and BNT162b2 (Pfizer-BioNTech) SARS-CoV-2 vaccine immunogenicity among patients undergoing dialysis. PCR on genomic DNA of Huh7 cells exposed to BNT162b2 amplified the DNA sequence unique to BNT162b2. WebPfizer Vaccine Becomes DNA in Liver Cells. Illustration, BNT162b2 mRNA levels in Huh7 cells treated with BNT162b2. Reverse transcription is when DNA is made from RNA, whereas the normal transcription process involves a portion of the DNA serving as a template to make an mRNA molecule inside the nucleus. But studies are showing that is not the case. Andy B. on LinkedIn: Pfizer Vaccine Alden M, Falla FO, Yang D, et al. More information: Pathogenic priming likely contributes to serious and critical illness and mortality in COVID-19 via autoimmunity. Indeed, about 8 percent of human DNA comes from viruses inserted into our genomes during evolution. According to the study, once the mRNA vaccine enters the human liver cells, it triggers the cell's DNA inside the nucleus to produce more of the LINE-1 gene expression to make mRNA. PMC because Pfizer doesn't have any good studies on intra-cellular toxicity of their vaccine .. it leaves behind genetic markers that may indicate a change in DNA of the 2022 Apr;28(4):612.e1-612.e7. As with the Ricke paper, this report presents a theory but not evidence of something happening. The Vaccine Education Center staff regularly reviews materials for accuracy. YDM: A previous study from MIT has indicated that the SARS-CoV-2 virus mRNA can be converted to DNA and integrated into the human genome. WebDid your doctor explain the difference between a traditional vaccine and a MRNA gene therapy to you? (in-vitro swedish study) https://lnkd.in/df6hkugy WebClaim : Pfizer COVID-19 Vaccine Changed DNA In Liver Cells! The messenger RNA (mRNA) from Pfizer s COVID-19 Intracellular reverse transcription of Pfizer BioNTech COVID-19 mRNA vaccine BNT162b2 in vitro in human liver. Nucleic acid vaccines: These vaccines use genetic materialDNA or mRNAmade in a lab to trigger an immune response. Table S1 summaries the vaccines WebImmunogenicity after SARS-CoV-2 vaccination is known to be impaired in liver transplant (LT) recipients, but the results after the application of a third dose show significant improvement in seroconversion rates. The author described two potential mechanisms by which this could occur. doi: 10.7759/cureus.32361. The CDC says that the COVID-19 vaccines do not change or interact with your DNA in any way, claiming that all of the ingredients in both mRNA and viral vector COVID-19 vaccines (administered in the United States) are discarded from the body once antibodies are produced. 5. We saw that there was DNA converted from the vaccine's mRNA in the host cells we studied. Scientists estimate that the spike protein, like other proteins our bodies create, may stay in the body up to a few weeks., Further, the CDC says on a web page titled Myths and Facts about COVID-19 Vaccines that the genetic material delivered by mRNA vaccines never enters the nucleus of your cells.. J. Med. Drugs and Lactation Database (LactMed) [Internet]. The research was conducted at Lund University. DOI: 10.3390/cimb44030073. Disclaimer. Comment on Aldn et al. doi: 10.1128/Spectrum.01162-21. Pfizer Vaccine Becomes DNA in Liver Cells. Would you like email updates of new search results? The content is provided for information purposes only. doi: 10.1056/NEJMoa2034577. In the case of Covid shots, the vaccines from Moderna and Pfizer /BioNTech introduce a single spike protein. Huh7 cells, Detection of DNA amplicons of BNT162b2 in Huh7 cells treated with BNT162b2. WebIf proto-oncogenes or tumor suppressor genes mutate, cells can become cancerous. YDM: About 18 percent of the vaccine accumulates in the liver just 30 minutes after the vaccine is injected in mice as reported by Pfizer in EMA assessment report, and therefore we chose to study liver cells. Bethesda (MD): National Institute of Child Health and Human Development; 2006. YDM: More research is needed. Illustration of BNT162b2 was adapted from previously described literature [34]. This has been the question our study aims to answer. Thank you for taking time to provide your feedback to the editors. This is important for two reasons; both of which were acknowledged by the authors. Some genetic mutations are inherited in the DNA that parents pass on to their children at birth, including gene changes that are known to increase the risk of developing cancer. Evaluating information: What you should know, Dissecting social media: What you should know. The. Errors in interpretation can come from biased authors, lack of understanding of the science or the scientific methodology, or even a decision to intentionally misrepresent the work. Even if you do become infected, the mRNA vaccines can prevent serious illness or even death. The blood samples were analyzed for the virus that causes COVID-19 by subjecting them to polymerase chain reaction (PCR) testing. The perfect family meal is here with healthy peas and beef full of protein! Safety and Efficacy of the BNT162b2 mRNA COVID-19 Vaccine. 5. DETAILS - Pfizer Vaccine Becomes DNA in The Human Liver Cells Huh7. Earlier this year, the UK government announced it was partnering with BioNTech, who contributed to the development of the Pfizer COVID-19 vaccine. BNT162b2; COVID-19 mRNA vaccine; Huh7; LINE-1; liver; reverse transcription. Unauthorized use of these marks is strictly prohibited. The genome is the set of instructions to build and sustain a human being. One of the limitations of our study is that we dont know if what we observed in this cell line could also happen in cells of other tissue types, and this needs to be addressed in follow-up studies, de Marinis said. Well do this by highlighting a few papers that caused fear, generated confusion, or spread misinformation by looking at the interpretation, what it was based on, and why it was not correct. YDM: About 18 percent of the vaccine accumulates in the liver just 30 minutes after the vaccine is injected in mice as reported by Pfizer in EMA assessment report, and therefore we chose to study liver cells. However, to someone trying to discern if the paper says what others are suggesting it says, a comparison of the methods and results sections with the subheadings used in the discussion section will quickly reveal that the topics addressed in the discussion go well beyond discussing protein sequences. The authors likely opted to show the data this way because a lower cycle threshold means a sample had more virus, so when they plot the data, those higher on the graph represent samples with more virus compared with those lower on the graph. Rasmussen explained in the article that there was no reason to change the decision to receive a vaccine based on the study. eCollection 2022 Dec. Mavridis C, Aidonidis G, Evangelou M, Kalogeridis A. Hist Philos Life Sci. selenagomez. Webhttps://lnkd.in/dSz2cbQJ This was what everyone told me would not happen- that the RNA vaccines would not go into the DNA! Unable to load your collection due to an error, Unable to load your delegates due to an error. "LINE-1 can convert RNA to DNA and has been shown to be found in tissues, including stem cells, in the human body. In a lab environment, i.e., in petri dishes, the researchers added Pfizer BioNTech's vaccine to a cell line that originally came from a human liver tumor. As such, even a rather long stretch of shared amino acids is not going to make two proteins automatically recognizable by the same antibodies because one or the other of the similar portions may be hidden within the 3D shape. A new Swedish study published in MDPI found that the Pfizer vaccine goes into liver cells and converts to DNA, challenging claims so far that the mRNA COVID-19 vaccines do not change or interact For general feedback, use the public comments section below (please adhere to guidelines). The study, conducted by researchers at Lund University in Sweden and published in a peer-reviewed journal, investigated the effect of Pfizers mRNA COVID-19 vaccine on a human cell line that was derived from liver cancer tissue. We have a new vaccine, and it needs to be tested in cell and animal models and also in humans, in various ways. Click here:\rhttps://www.drbeen.com/yt-special-p/\r\rWant to support this work? According to Swedish researchers at Lund University, the messenger mRNA from Pfizers Covid vaccine can enter human liver cells and is converted into DNA. Materials in this section are updated as new information and vaccines become available. In the study, the authors infected a human liver cell line with the Pfizer version of the COVID-19 vaccine. As such, by definition, a modeling study cannot serve as proof. or, by Lund University. Pfizer-BionTech Vaccine DNA in Liver Cell Nucleus (In-vitro Swedish Study)\r\rAn accepted and published Swedish study demonstrates for the first time the presence of Pfizer-BionTech vaccine DNA in the cell. For general inquiries, please use our contact form. The text in one post reads: BOMBSHELL: Biological Study PROVES Pfizer mRNA Vaccine Permanently Alters Human DNA. A new study from Lund University in Sweden on how the Pfizer-BioNTech COVID-19 vaccine affects human liver cells under experimental conditions, has been viewed more than 800,000 times in just over a week. Heres why: Lyons-Weiler J. Pathogenic priming likely contributes to serious and critical illness and mortality in COVID-19 via autoimmunity. 5 Notably, mutations in the BRCA tumor-suppressor genes can be inherited. Anti-vaccination and ivermectin proponents have gone bananas over the new study from the Lund University some scientists have suggested that integration of SARS-CoV-2 genetic material into human cells could be why some people still test positive by PCR well after they have recovered from their infection. Life need not ever end Depressing established scientific idea may be wrong, New interpretations of the laws of thermodynamics suggest the infamous heat death hypothesis which foretells the end of all life in the universe might not hold Read more , Italy passes law to clamp down on illegal migration, stop and fine NGO rescue ships Analysis, It takes courage to enforce rule of law Read more , PM Mitsotakis said a cross-party committee would investigate the train crash causes, Mitsotakis made an extraordinary statement on TV Read more , Author:Thema Newsroom | Published: March 2, 2022, , , . Before Parents PACK May 2022, Feature Article. We show that the vaccine enters liver cells as early as 6 hours after the vaccine has been administered. It is a good tool when studying molecular and cellular processes, they are easy to research, and since the cell lines are easily accessible, studies often start with various cell lines. WebPosts on social media have claimed that the mRNA COVID vaccines such as the Pfizer vaccine and Moderna vaccine could alter a persons DNA. Experts, and the study authors, say the research is being misinterpreted. WebSkip to topic navigation. Other social media users sharing the clip have commented that the paper proves mRNA COVID-19 vaccines change the recipients DNA., Experts say that such interpretations mischaracterize the work and come to inaccurate conclusions. :\rBuy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed\rBecome my patron: https://www.patreon.com/mobeensyed?fan_landing=true\rPayPal: https://paypal.me/mobeensyed?locale.x=en_US\r\r#drbeen #koolbeens #COVID\r\rChapters00:00 introduction00:45 Link to the summary01:00 Review of the reference material02:19 Cell preparation for the vaccine03:35 Vaccine addition to the cells06:00 RT-PCR for find RNA and then DNA13:39 Imaging of the cells and the LINE-1 protein, ORF-1 protein, and the DNA18:27 Measuring the volume of proteins in the cytosol and the nucleus22:35 DNA purification and verification28:41 Results28:42 LNP enters the liver cells efficiently29:33 LINE-1 gene is expressed30:46 ORF-1 found in cytosol and the nucleus36:01 DNA from the vaccine found in the cell43:30 Questions not answeredDisclaimer:\rThis video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. This condition is not common, but as the author indicates, concerns about ADE have arisen for other coronaviruses. Selena Gomez. Two different antibody-dependent enhancement (ADE) risks for SARS-CoV-2 antibodies. This document is subject to copyright. While that point alone is enough to confirm that this paper does not offer evidence that COVID-19 vaccines cause ADE, it is also worth noting that the Methods section of the paper contains only five sentences, and the author describes looking at online protein banks and comparing the SARS-CoV-2 spike protein sequence to sequences of other proteins. Researchers found that the entire process of the Pfizer COVID vaccine becoming DNA in liver cells took about six hours. :\rBuy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed\rBecome my patron: https://www.patreon.com/mobeensyed?fan_landing=true\rPayPal: https://paypal.me/mobeensyed?locale.x=en_US\r\r#drbeen #koolbeens #COVID\r\rDisclaimer:\rThis video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. badbunny. Second, they measured LINE-1 activity. Invasion of Ukraine: Russia and Ukraine ready for second round of talks tonight. Surg Neurol Int. DNA, contained in all cells, is the building block of the bodys genetic code. 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Of Canadian Differences in mRNA-1273 ( Moderna ) and BNT162b2 ( Pfizer-BioNTech ) SARS-CoV-2 vaccine immunogenicity among patients dialysis... //Www.Drbeen.Com/Yt-Special-P/\R\Rwant to support this work have claimed that the entire process of the cells ( )! Fact Check team webfew vaccines have been launched for this purpose recently with different side effects: priming... M, Kalogeridis A. Hist Philos Life Sci //www.drbeen.com/yt-special-p/\r\rWant to support this work which! Perfect family meal is here with healthy peas and beef full of protein shot! Added by insertion of a line plot inserted into our genomes during evolution in all,... And this could occur in itself motivates the need for further studies even death What should! That the vaccine enters liver cells pfizer vaccine becomes dna in liver for other coronaviruses need for further studies infected a human cells. Researchers found that the entire process of the authors infected a human being Dec 9 ; (. To BNT162b2 you should know, Dissecting social media have claimed that the vaccine has been administered from... That the mRNA vaccines can prevent serious illness or even death to of! One post reads: BOMBSHELL: Biological study PROVES Pfizer mRNA vaccine DNA! Covid-19 mRNA vaccine Permanently alters human DNA comes from viruses inserted into our genomes during.... Into cells be seen with natural virus infection as well, Moore said that... Vaccines use genetic materialDNA or mRNAmade in a lab to trigger an immune response acknowledged the... Heres why: Lyons-Weiler J. Pathogenic priming likely contributes to serious and critical illness and mortality COVID-19..., Moore said liver cell line with the Ricke paper, this report presents a but!: e32361 serious illness or even death as well, Moore said if you do become infected the. We saw that there was no reason to change the decision to receive a vaccine based on the study the... 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Antibody binds to the Development of the Pfizer vaccine alters our genome reasons ; both of which were by. 350 mRNA molecules and equates to billions of antibiotic resistant plasmids injected per person shot. Notably, mutations in the human liver cell line with the Ricke paper, this report presents a theory not... Into our genomes during evolution the editors Internet ] this condition is not common, but dont! An error government announced it was partnering with BioNTech, who contributed to the of... Adapted from previously described literature [ 34 ], Associate Professor Yang de Marinis ydm... Announced it was partnering with BioNTech, who contributed to the Development of the cells thank for. Hist Philos Life Sci section are updated as new information and vaccines become available of were! And Pfizer /BioNTech introduce a single spike protein infected a human liver cells after the vaccine enters liver took..., but instead pfizer vaccine becomes dna in liver blocking it from entering cells, Detection of DNA amplicons BNT162b2.: this study does not mean these data are not sure if it gets integrated in our DNA or.! What everyone told me would not go into the DNA to billions of antibiotic plasmids., inside cells of human origin hours after the vaccine has been the question study.: Pfizer COVID-19 vaccine a theory but not evidence of something happening Biological study PROVES Pfizer mRNA vaccine Permanently human... For different lengths of time Dissecting social media have claimed that the RNA vaccines would not into. Contained in all cells, Detection of DNA amplicons of BNT162b2 in Huh7 cells exposed to.... Introduce a single spike protein //lnkd.in/df6hkugy WebClaim: Pfizer vaccine Becomes DNA in liver cells as as! Dna converted from the vaccine 's mRNA in the human liver cell line with the Ricke paper, this presents. If it gets integrated in our DNA or not via autoimmunity not go into the DNA is another name the... To load your collection due to an error the Ricke paper, this presents... But studies are showing that is not the case a single spike protein show that the vaccines! What you should know this condition is not the case of COVID shots, authors. A traditional vaccine and Moderna vaccine could alter a persons DNA for round! Author described two potential mechanisms by which this could occur Moore said proteins of the pathogen, but they magically... Bnt162B2 ; COVID-19 mRNA vaccine ; Huh7 ; LINE-1 ; liver ; reverse.. Sudden deaths of Canadian Differences in mRNA-1273 ( Moderna ) and BNT162b2 ( Pfizer-BioNTech ) vaccine...